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  • Title: [Effectiveness of cefotetan in clinical practice].
    Author: Vinogradova MA, Kozko TD, Petukhov EM, Shubina VA, Shneĭter II, Miroshina TI, Vinogradov NA, Astaf'eva TA, Astakhova ZN, Bokov IB, Rogovaia KI, Maksimova VI, Petrushina VS, Predtechenskaia TI.
    Journal: Antibiot Khimioter; 1997; 42(7):16-9. PubMed ID: 9334142.
    Abstract:
    Forty five patients at the age of 15 to 84 years with signs of infection requiring active antibacterial therapy were treated with cefotetan. In the majority of the patients pulmonary affections such as double pneumonia, pleurisy or bronchopneumonia were stated. In some patients bronchopulmonary pathological processes were associated with pancreatitis, cholecystitis or other diseases of the gastrointestinal tract. A separate group included patients with diseases of the small pelvis organs (pelvioperitonitis, metroendometritis or prostatitis) and diseases of the urogenital system (pyelonephritis) arachnoiditis. In all the patients except for one with bronchopneumonia at the background of chronic myeloleukemia and agranulocytosis the results of the treatment were good and satisfactory. Cefotetan proved to be efficient in the treatment of purulent affections of the skin and subcutaneous fat (abscesses and phlegmona), trophic disturbances at the background of pathological processes in the vessels and pyoseptic condition. Cefotetan practically had no side effects. Only in 2 patients insignificant nausea during the first 2 days of the treatment was recorded. In some patients the antibiotic intramuscular injections were painful with formation of cold infiltrates. After intravenous administration of cefotetan no adverse reactions were observed.
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