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  • Title: [Contrast media-associated nephropathy--pathogenesis and prevention].
    Author: Erley CM, Duda SH.
    Journal: Aktuelle Radiol; 1997 Jul; 7(4):189-92. PubMed ID: 9340015.
    Abstract:
    Contrast media-associated nephrotoxicity continues to be a relevant cause of acute renal failure, especially in patients with pre-existing renal insufficiency. Alterations in renal hemodynamics and direct tubular toxicity by contrast media are the primary factors believed to be responsible for contrast media-associated nephrotoxicity. We review recent insights into the pathogenesis of this complication and summarize prophylactic strategies focussing on hydration, vasoactive pharmacological agents, and prophylactic hemodialysis'.
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