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  • Title: [Use of a new water-soluble aldosterone-antagonist in surgery. Early clinical results].
    Author: Nahum M, Ratto GB, Motta G.
    Journal: Minerva Med; 1976 Apr 21; 67(19):1263-75. PubMed ID: 934482.
    Abstract:
    A new i.v., water-soluble aldosterone antagonist (potassium canrenoate) was employed for the first time in a series of patients operated for various forms of abdominal disease. The pharmacological and clinical effects of the drug were constantly reproduced and a marked anti-aldosterone activity was noted. The drug is felt to be specifically indicated in the management of secondary hyperaldosteronism typical of the immediate postoperative period.
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