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Title: Acidosis, local anesthetics, and the newborn. Author: Brown WU, Bell GC, Alper MH. Journal: Obstet Gynecol; 1976 Jul; 48(1):27-30. PubMed ID: 934571. Abstract: Four newborn infants were studied following maternal epidural block with lidocaine or mepivacaine. Each of these neonates, born with a pH of 7.23 or below in the umbilical vein blood, showed an elevated fetal-to-maternal concentration ratio, a possible manifestation of ion trapping of a weak base.[Abstract] [Full Text] [Related] [New Search]