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  • Title: Presynaptic inhibition compared with homosynaptic depression as an explanation for soleus H-reflex depression in humans.
    Author: Kohn AF, Floeter MK, Hallett M.
    Journal: Exp Brain Res; 1997 Sep; 116(2):375-80. PubMed ID: 9348136.
    Abstract:
    The H-reflex is depressed for seconds if elicited following a single H-reflex or train of H-reflexes. Presynaptic inhibition from flexor afferents (tibialis anterior) onto soleus Ia afferents elicited by either single or trains of stimuli had no effect on the soleus H-reflex on a time scale of seconds. Postsynaptic inhibition was also excluded by magnetic stimulation tests that showed that the excitability of the motoneuron pool was not changed at latencies within a range of seconds. Homosynaptic depression localized at the presynaptic terminal seems to be the mechanism behind the H-reflex depression in humans.
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