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  • Title: Studies on aminophenazone and phenobarbital release from suppositories prepared on different bases.
    Author: Piasecka H, Zakrzewski Z.
    Journal: Pol J Pharmacol Pharm; 1976; 28(2):199-203. PubMed ID: 934948.
    Abstract:
    Employing in the studies in vitro the dynamic system, we investigated aminophenazone (APH) and phenobarbital (PHB) release through semipermeable membrane from suppositories prepared on different bases, namely. Massupol, Oleum Cacao, H-15 Witepsol, Imhausen Suppositorien Masse SB, 1500 polioxyethylene glycol. The rate of APH liberation was highest from Imhausen and lowest from H-15 Witepsol; PHB was released most rapidly from Oleum Cacao, the poorest results being observed in the case of polioxyethylene glycol.
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