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Title: The multi-talented beta-catenin makes its first appearance. Author: Shapiro L. Journal: Structure; 1997 Oct 15; 5(10):1265-8. PubMed ID: 9351813. Abstract: beta-catenin plays a central part in cell adhesion as a structural component of the cadherin complex. In a seemingly disparate role, it is also important in embryo patterning, and now has emerged as a leading actor in carcinogenesis. beta-catenin achieves its diverse functions by interacting with many partners. The recent structure of the core domain from beta-catenin suggests how this talented molecule can achieve its many functions.[Abstract] [Full Text] [Related] [New Search]