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  • Title: Measurement of suberythema UVA radiation effects on skin by 31P magnetic resonance spectroscopy.
    Author: Zemtsov A.
    Journal: Photodermatol Photoimmunol Photomed; 1997; 13(1-2):24-6. PubMed ID: 9361125.
    Abstract:
    31P magnetic resonance spectroscopy (MRS) scans were obtained from the same anatomical location in four healthy Caucasian individuals before and after 1/2 MED UVA radiation. Suberythema UVA radiation induced in skin production of phosphomonoesters, phosphodiesters, and also depleted phosphocreatine and adenosine triphosphate (ATP). This data seems to indicate that 31P MRS is a sensitive enough technique to detect UVA induced changes in skin phosphometabolites. Furthermore, this data also appears to indicate that suberythema UVA radiation and dexamethasone induce in skin nearly identical pharmacodynamic effect.
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