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  • Title: The metabolism of isopropylantipyrine in the rat and man.
    Author: Tateishi M, Shimizu H.
    Journal: Xenobiotica; 1976 Apr; 6(4):207-15. PubMed ID: 936642.
    Abstract:
    1. The major urinary metabolite of isopropylantipyrine in the rat and man was an enol glucuronide of N-desmethyl isopropylanipyrine, which comprised about 80% of the whole urinary metabolites. 2. Six other minor metabolites occurred in rat urine; all lacked the N-methyl group of the parent drug, and some had undergone further oxidation at the isopropyl group, the phenyl group or in the C-4 position.
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