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  • Title: [Cutaneous B-cell lymphoma with aggressive clinical presentation: apropos of a case].
    Author: Grau E, Real E, Perella M, Escandon J, Pastor E, Gómez A.
    Journal: Sangre (Barc); 1997 Jun; 42(3):231-3. PubMed ID: 9381268.
    Abstract:
    A patient with an atypical clinical presentation of cutaneous B-cell lymphoma is reported. He showed a rapidly growing tumour with areas of skin necrosis, haemorrhage, ulceration and suppuration in his upper back. There were involvement of contiguous anatomic site and extracutaneous spread. The histology showed diffuse lymphoid infiltration of the dermis. The cell morphology was that of a monotonous population of centroblasts. Treatment with CHOP and radiotherapy provided long-term complete remission. This case illustrates that primary cutaneous B-cell lymphoma may behave as a high-grade malignancy. Vigorous treatment with chemotherapy and radiotherapy is recommended in such cases.
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