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  • Title: PDZ domain proteins: scaffolds for signaling complexes.
    Author: Ranganathan R, Ross EM.
    Journal: Curr Biol; 1997 Dec 01; 7(12):R770-3. PubMed ID: 9382826.
    Abstract:
    InaD, a Drosophila photoreceptor scaffolding protein, assembles multiple signal-transducing proteins at the membrane via its five PDZ domains, enhancing speed and efficiency of vision. Extensive conservation of PDZ domains suggests that these motifs have a general role in organizing diverse signaling complexes.
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