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  • Title: Spontaneous pneumomediastinum in a patient with bronchiolitis obliterans after bone marrow transplantation.
    Author: Galanis E, Litzow MR, Tefferi A, Scott JP.
    Journal: Bone Marrow Transplant; 1997 Oct; 20(8):695-6. PubMed ID: 9383235.
    Abstract:
    After allogeneic bone marrow transplantation for chronic myelogenous leukemia, spontaneous pneumomediastinum and subcutaneous emphysema developed in a patient with bronchiolitis obliterans. Computed tomography scanning of the chest failed to reveal the cause. There was no evidence of a pulmonary process, pneumothorax, or pharyngeal or upper airway leak. Despite the alarming appearance of the patient, conservative management, including high-flow oxygen, resulted in resolution of the pneumomediastinum and subcutaneous emphysema. The cause of pneumomediastinum and subcutaneous emphysema in bone marrow transplant recipients is discussed.
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