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  • Title: The effects of imidazoacridinones, new antineoplastic agents, on the human erythrocyte membrane.
    Author: Jóźwiak Z, Pacholska M, Szwarocka A.
    Journal: Biochem Mol Biol Int; 1997 Nov; 43(4):883-90. PubMed ID: 9385448.
    Abstract:
    In the present study, the interactions of imidazoacridinones, C-1311 and C-1371 with human erythrocyte membranes were examined by electron spin resonance spectroscopy (ESR). It was observed that both compounds C-1311 and C-1371 preferentially bind to proteins producing the conformational changes of erythrocyte membrane skeletal proteins.
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