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  • Title: Saniculoside N from Sanicula europaea L.
    Author: Arda N, Gören N, Kuru A, Pengsuparp T, Pezzuto JM, Qiu SX, Cordell GA.
    Journal: J Nat Prod; 1997 Nov; 60(11):1170-3. PubMed ID: 9392884.
    Abstract:
    Extracts from the aerial parts of Sanicula europaea L. were investigated for their anti-HIV activity, and the 50% ethanolic extract was shown to exhibit the highest activity. A new triterpene saponin glycoside, 21 beta-(angeloyloxy)-3-O-[beta-D-arabinopyranosyl(1-->4)-beta- D-glucopyranosyl (1-->3)-beta-D-glucuronopyranosyl propyl ester]-3 beta,15,16,22 alpha,28 beta-pentahydroxy-delta(12)-oleanene, saniculoside N (1), in addition to the known phenolic acids, rosmarinic acid (2), and caffeic acid (3) were isolated as major components. Rosmarinic acid was established as the principal active substance.
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