These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: [Acetaldehyde adducts in the cerebral cortex of ethanol-fed mice].
    Author: Iwahashi K, Itoh M, Nakamura K, Ameno K, Suwaki H, Takeuchi Y.
    Journal: Nihon Arukoru Yakubutsu Igakkai Zasshi; 1997 Oct; 32(5):489-94. PubMed ID: 9396224.
    Abstract:
    To investigate the neurotoxicity of acetaldehyde covalent adducts, immunohistochemical staining for acetaldehyde adducts using the antibody against acetaldehyde adducts, was performed in the cerebral cortex of ethanol-fed (withdrawal) mice. In the ethanol-fed mice, the degeneration in the cerebral cortex was found, while the protein epitope related to acetaldehyde was found in the cerebral cortex, liver and adrenal cortex. No histochemical and immunohistochemical changes in the tissues from the control mice were found. It is possible that acetaldehyde adducts may effect on the cerebral cortex as the neurotoxicity which cause psychosis such as delirium and hallucination after alcohol drinking.
    [Abstract] [Full Text] [Related] [New Search]