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  • Title: Monitoring of nonspecific cell-mediated immunity in cancer patients. I. Frequent dissociation between the responses of skin tests to recall antigens and in vitro lymphocyte transformation.
    Author: Simmler MC, Rameau G, Chou MJ, Mathé G.
    Journal: Isr J Med Sci; 1976; 12(4-5):472-8. PubMed ID: 939695.
    Abstract:
    No correlation was found between in vivo delayed hypersensitivity responses in cancer patients and in vitro lymphocyte transformation by mitogens or antigens, even when the same antigen [purified protein derivative of tuberculin (PPD)] was used for both the in vivo and in vitro testing. However, there was a good correlation between the in vitro lymphocyte transformation tests with PPD and with the mitogens phytohemagglutinin and pokeweed mitogen.
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