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  • Title: Chlamydia pneumoniae in children with otitis media.
    Author: Storgaard M, Ostergaard L, Jensen JS, Farholt S, Larsen K, Ovesen T, Nødgaard H, Andersen PL.
    Journal: Clin Infect Dis; 1997 Nov; 25(5):1090-3. PubMed ID: 9402363.
    Abstract:
    In this study the polymerase chain reaction was used to test for the presence of Chlamydia pneumoniae DNA in 118 middle-ear aspirates from 20 children with acute otitis media (AOM) and 53 children with otitis media with effusion (OME). C. pneumoniae was detected in 8 samples obtained from 5 children with OME and, together with Streptococcus pneumoniae, in a sample from 1 child with AOM. The mean age of these five children (6.6 +/- 1.4 years) was significantly higher than that of the 48 children with OME in whom C. pneumoniae could not be detected (4.3 +/- 1.9 years). The presence of C. pneumoniae in 9.4% of the examined children with OME suggests that C. pneumoniae might be a significant supplementary factor in the etiology of this common children's disease.
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