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  • Title: Ocular palsies in the absence of other neurological or ocular symptoms: analysis of 105 cases.
    Author: Batocchi AP, Evoli A, Majolini L, Lo Monaco M, Padua L, Ricci E, Dickman A, Tonali P.
    Journal: J Neurol; 1997 Oct; 244(10):639-45. PubMed ID: 9402541.
    Abstract:
    We studied prospectively 105 unselected patients complaining of ptosis and/or diplopia due to extrinsic ophthalmic muscle palsies without other neurological signs. All patients underwent the same diagnostic protocol. The presenting symptoms were: ptosis, 35 patients (33%); diplopia, 27 patients (26%); ptosis and diplopia, 43 patients (41%). The oculomotor nerve was most frequently involved, followed by the abducens nerve. The final diagnoses were: ocular myasthenia, intracranial and/or orbital pathology, thyroid ophthalmopathy, diabetic ophthalmoplegia, mitochondrial myopathy, oculopharyngeal muscular dystrophy. In 26 patients (25%) the cause remained undetermined. Our study confirms the difficulty of establishing an aetiological diagnosis in patients with isolated ocular palsies.
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