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  • Title: Radical hysterectomy with or without preoperative radium for stage IB squamous cell carcinoma of the cervix.
    Author: Surwit E, Fowler WC, Palumbo L, Koch G, Gjertsen W.
    Journal: Obstet Gynecol; 1976 Aug; 48(2):130-3. PubMed ID: 940643.
    Abstract:
    A retrospective study of 119 patients ranging from 30 to 69 years of age was undertaken to evaluate the effectiveness of preoperative radium treatment for patients with Stage IB (FIGO 1971) squamous cell carcinoma of the cervix undergoing radical hysterectomy. Results in 61 patients who had radical hysterectomy without preoperative radium treatment were compared to those in 58 patients who had received radium preoperatively. The patients receiving radium systems had an uncorrected 5-year survival rate of 89.7%, while the patients without preoperative radium treatment had a 75.1% 5-year rate of survival. This difference in survival rate was judged to be secondary to the greater incidence of lymphatic invasion and residual tumor in the surgical specimens of the patients who did not receive preoperative radium. The occurrence of significant gastrointestinal and urinary tract complications was identical in the 2 groups.
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