These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Nonsymmetrically substituted cyclic urea HIV protease inhibitors.
    Author: Wilkerson WW, Dax S, Cheatham WW.
    Journal: J Med Chem; 1997 Dec 05; 40(25):4079-88. PubMed ID: 9406598.
    Abstract:
    A series of nonsymmetrically substituted cyclic ureacarboxamides was synthesized and evaluated for antiviral activity as a function of the inhibition of HIV-protease. Selected protease inhibitors were also evaluated for oral bioavailability. The synthesis, pharmacology, quantitative structure-activity relationship (QSAR), and pharmacokinetics for the series will be discussed.
    [Abstract] [Full Text] [Related] [New Search]