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  • Title: Frequency specificity of the human auditory brainstem and middle latency responses to brief tones. II. Derived response analyses.
    Author: Oates P, Stapells DR.
    Journal: J Acoust Soc Am; 1997 Dec; 102(6):3609-19. PubMed ID: 9407654.
    Abstract:
    This study investigated the frequency specificity of the auditory brainstem (ABR) and middle latency (MLR) responses to 500- and 2000-Hz brief tones using narrow-band derived response analyses of the responses recorded in high-pass masking noise [Oates and Stapells, J. Acoust. Soc. Am. 102, 3597-3608 (1997)]. Stimuli were linear- and exact-Blackman-gated tones presented at 80 dB ppe SPI. Cochlear contributions to ABR wave V-V' and MLR wave Na-Pa were assessed by response amplitude profiles as a function of derived band center frequency. The largest amplitudes of waves V and Na-Pa occurred in the 500- and 707-Hz derived bands in response to the exact-Blackman- and linear-gated 500-Hz tones. The peak in the response amplitude profiles for wave V to both 2000-Hz stimuli was seen in the 2000-Hz derived band. For wave Na-Pa, the maxima in the amplitude profiles occurred in the 2000- and 1410-Hz derived bands for the exact-Blackman- and linear-gated tones. Smaller cochlear contributions to the ABR/MLR were also present at 0.5-1 octave above and below the nominal stimulus frequencies. The ABR/MLR to 500- and 2000-Hz 80 dB ppe SPL tones thus shows good frequency specificity, with no significant differences in the frequency specificity of: (1) ABR versus MLR; (2) these evoked potentials to 500-versus 2000-Hz tones; and (3) responses to exact-Blackman- versus linear-gated tones.
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