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  • Title: [Paget's disease of the breast].
    Author: Napoli L, Pagano A, Comparetto S, Giammanco M, Romano G, Romano G.
    Journal: Minerva Chir; 1997; 52(7-8):927-31. PubMed ID: 9411294.
    Abstract:
    Paget's disease of the nipple is a rare lesion that is not always associated with underlying breast cancer. The authors report three cases of Paget's disease; in two of the three patients examined, the disease became evident following the appearance of an erythematous and erosive lesion on the nipple and areola, but no clinical evidence of an underlying nodule. In both cases diagnosis was made by integrating cytological tests by apposition of the nipple with mammography. In the third case the disease became manifest following the onset of a lesion on the nipple and areola with the characteristics of chronic eczema in association with a retroareolar nodule, measuring 3 cm, with the mammographic characteristics of an infiltrating carcinoma. All three patients were treated by radical mastectomy modified according to Madden.
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