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  • Title: [The possible connection between immunoglobulin levels in the blood and human susceptibility to dysentery].
    Author: Khazenson LB, Sholud'ko GS, Nikolaeva TA.
    Journal: Zh Mikrobiol Epidemiol Immunobiol; 1976 May; (5):89-94. PubMed ID: 941610.
    Abstract:
    A determination was made of the immunoglobulin G, M and A concentration in the blood serum of women suffering from dysentery and other acute intestinal diseases, those who sustained the disease and healthy persons (259 in all). Probability of detection of low IgA concentrations in the patients was 7-12 times greater during the first days of the disease than in healthy persons; IgG And IgM levels in the patients who sustained the disease and in healthy individuals showed no significant difference. Possible relationship between the synthesis of the secretory IgA in the intestine and the blood serum IgA level was discussed; however, a conclusion on a possibility of detection of persons most susceptible to dysentery and other acute intestinal diseases by the low serum IgA level could be made only after further investigations.
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