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  • Title: [Bilateral nephrectomy before renal transplantation in autosomal dominant polycystic renal disease].
    Author: Schillinger F, Montagnac R, Jourdan AL, Massia D, Brandt B, Toupance O, Chanard J.
    Journal: Nephrologie; 1997; 18(5):181-6. PubMed ID: 9424595.
    Abstract:
    Patients with autosomal dominant polycystic kidney disease are good candidates for renal transplantation, despite the fact that they are older at initiation of dialysis treatment. After grafting, the native polycystic kidneys are, however, at risk of infectious and hemorrhagic complications, in addition to patient's discomfort and technical difficulties with graft placement. We report on 10 successful cases of pretransplant binephrectomy performed in one time and analyse the risk factors of such a surgery. Nowadays, it appears that the disadvantages of an anephric state can be balanced by substitutive therapy. In conclusion, after this short series, we think that bilateral nephrectomy has to be considered in patients with autosomal polycystic kidney disease, especially when they have a prior history of renal infections and/or repeated hematurias.
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