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  • Title: The pulmonary absorption-excretion volume effect.
    Author: Rackow H, Salanitre E.
    Journal: Anesth Analg; 1976; 55(1):51-6. PubMed ID: 942830.
    Abstract:
    An in-vitro experiment demonstrated the concentration effect of N2O (3% versus 75%) during elimination and during uptake. Other pulmonary absorption-excretion phenomena also occur simultaneously, as paired events during uptake and then during elimination:diffusion hyperoxia and diffusion anoxia; alveolar concentration of CO2, and alveolar dilution of CO2. These clinical phenomena, as well as the second gas effect, are all related, and the pulmonary absorption-excretion volume is found to depend in part on the type of ventilation:volume controlled, pressure controlled, or spontaneous respiration.
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