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  • Title: Tuberculosis in Lorraine, France: study of prognostic factors.
    Author: Rabaud C, Engozogho M, Dailloux M, Hoen B, May T, Canton P.
    Journal: Int J Tuberc Lung Dis; 1997 Jun; 1(3):246-9. PubMed ID: 9432371.
    Abstract:
    AIM: To identify factors predicting short-term mortality in patients with tuberculosis in the Lorraine region of France. METHOD: Retrospective survey in nine voluntarily participating hospitals between January 1990 and December 1994. RESULTS: In total 351 files were analyzed. The average age of patients was 49 +/- 19 years; 77% were of French origin, 60% were male; 35% were in paid employment at the time of the diagnosis, 42% were unemployed and 23% were retired. Twenty-three patients were infected by the human immunodeficiency virus (HIV), and 34 patients had a prior history of tuberculosis; 79% of all cases were exclusively pulmonary, 14% were exclusively extra-pulmonary (more frequent in women) and 7% were mixed. Extra-pulmonary sites of involvement were more frequent in HIV-infected patients. Chest X-ray was suggestive of tuberculosis in 158 patients with pulmonary involvement, and non-suggestive in 145 (more frequently in HIV-infected patients). In univariate analysis, HIV co-infection, increasing age and unemployment were linked to death during treatment. In multivariate analysis (logistic regression), HIV co-infection, old age, unemployment, pulmonary involvement and French origin were significantly linked to the risk of death during treatment.
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