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  • Title: [Preoperative radiotherapy in cancer of the rectum. Our 5-year experience].
    Author: Manenti A, Gavioli M, Santantonio M, Parmiggiani M, Mandolini G, Falchi A, Miselli R, Gabrielli C, Luppi G, Rosi AC, Piccagli I, Romani M.
    Journal: Minerva Chir; 1997 Sep; 52(9):1029-34. PubMed ID: 9432576.
    Abstract:
    Since 1990, 41 patients with rectal carcinoma have been submitted to preoperative radiotherapy, which induced a shrinkage of the tumor, favouring its surgical resection. Besides, in 3 cases the operative specimens were tumor free, and a higher incidence of A and B 1 categories was found. Surgical results have been compared with an analogous group of 20 patients, where surgery was performed as a first procedure, then followed by radiotherapy in 9. No increase of postoperative complications was observed. While analysis of follow-up results demonstrates a decrease of tumour recurrence in patients with preoperative radiotherapy, no difference in survival was registered, because of the development of extra-pelvic metastases.
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