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  • Title: [Clinical and laboratory diagnosis of heart disease in systemic lupus erythematosus].
    Author: Alves LJ, Hydalgo L, Rolim LF, Campagnone GZ, Aidar MT, Novaes GS, Kalil G.
    Journal: Arq Bras Cardiol; 1997 Feb; 68(2):79-83. PubMed ID: 9433831.
    Abstract:
    PURPOSE: To examine heart disease in the systemic lupus erythematosus (SLE) and the association of cardiac abnormalities with anticardiolipin antibodies (ACL). METHODS: Sixteen patients with active SLE disease (group I) were compared with 14 patients without disease activity (group II). A control group of 10 healthy subjects were also evaluated. Patients were subjected to cardiovascular history and physical examination as well as electrocardiogram, thoracic x-ray, two-dimensional and Doppler echocardiogram, and ACL serum determination (ELISA). RESULTS: Myocardial disease characterized by tachycardia, heart failure or echocardiographic abnormalities was shown by 75% of patients in the group I. It was associated with ACL positive in 27.2% of these patients. Pericardial and valvular involvement were observed in 25% of patients in group I. Group II showed myocardial involvement in 21.4% of patients without positive ACL. CONCLUSION: Myocardial disease was the most frequent heart involvement in active SLE, and we did not found any association between SLE heart disease and positive anticardiolipin antibodies.
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