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  • Title: Injected nuclei in frog oocytes provide a living cell system for the study of transcriptional control.
    Author: Gurdon JB, De Robertis EM, Partington G.
    Journal: Nature; 1976 Mar 11; 260(5547):116-20. PubMed ID: 943701.
    Abstract:
    Human HeLa nuclei injected into Xenopus oocytes synthesise RNA continuously for up to 1 month, and some of this RNA is translated into HeLa proteins. Nuclear proteins extracted from other cells enter the injected nuclei. This living cell system can be used for the study of transcriptional controls.
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