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  • Title: Plasma concentrations of 13,14-dihydro-15-keto-prostaglandin F during pregnancy in sheep.
    Author: Mitchell MD, Flint AP, Turnbull AC.
    Journal: Prostaglandins; 1976 Feb; 11(2):319-29. PubMed ID: 944462.
    Abstract:
    A specific and sensitive radioimmunoassay is decribed for 13,14-dihydro-15-keto-prostaglandin F in ovine plasma. Using this assay it has been shown that, in sheep, jugular venous 13,14-dihydro-15-keto-prostaglandin F concentrations increase at parturition and correlate well with concentrations of prostaglandin F in the utero-ovarian vein. It is suggested that uterine prostaglandin F production under these conditions may be assessed by measuring peripheral venous 13,14-dihydro-15-keto-prostaglandin F, thereby avoiding the need for chronic utero-ovarian venous catheters.
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