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  • Title: Fanconi's anemia: the preanemic phase.
    Author: McIntosh S, Breg WR, Lubiniecki AS.
    Journal: Am J Pediatr Hematol Oncol; 1979; 1(2):107-10. PubMed ID: 94509.
    Abstract:
    Anticipation of Franconi's anemia prior to the development of overt marrow aplasia may prevent some morbidity and mortality from infectious and hemorrhagic complications. A presumptive diagnosis was made in a firstborn child and radial anomalies, small size, elevated fetal hemoglobin, intermittent excessive chromosome breakage and elevated T-antigen expression in fibroblasts infected with Simian virus 40. Serial studies may help identify infants and young children at risk to develop this type of constitutional marrow hypoplasia.
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