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  • Title: Comparison of the effect of two heights of glycine irrigation solution on serum sodium and osmolality during transurethral resection of the prostate.
    Author: van Renen RG, Reymann U.
    Journal: Aust N Z J Surg; 1997 Dec; 67(12):874-7. PubMed ID: 9451346.
    Abstract:
    BACKGROUND: The absorption of sodium-deficient, hypotonic irrigation solution is believed to contribute, in certain cases, to hyponatraemia and hypo-osmolality and, in severe cases, to the so-called transurethral resection of the prostate (TURP) syndrome. METHODS: The effect of the height of 1.5% glycine irrigation solution during intermittent-flow TURP on serum sodium and osmolality was studied peri-operatively in 40 patients. The height of the glycine was set at 70 (n = 20) or 150 (n = 20) cm above the operating table. RESULTS: We found no statistically significant difference in the measured serum sodium (P = 0.929) and osmolality (P = 0.260) values between the two groups during the 24 hr study period. CONCLUSIONS: The height of the irrigation solution is not important in the development of hyponatraemia and hypo-osmolality, and other factors are probably more important.
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