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  • Title: [A change in the state of neurons of the arcuate region of the hypothalamus in different stages of the sexual cycle in rats].
    Author: Babichev VN, Ignatkov VIa.
    Journal: Fiziol Zh SSSR Im I M Sechenova; 1976 Apr; 62(4):516-24. PubMed ID: 945200.
    Abstract:
    With the help of microionophoretic stimulation of individual neurons of the arcuate region of the hypothalamus and the registration of its activity, changes in the sensitivity to dopamine during several stages of the sexual cycle of rats was studied. It was shown that in the 1st half of the day of proestrus the majority of neurons of the arcuate region, in correspondance to the increase in the level of estrogens in the blood plasma during this phase of the cycle, were activated by microionophoretic injections of dopamine. In the 2nd half of the day of proestrus, when the level of estrogens is minimal, and in the Diestrous-2 stage, it was observed that among registered neurons, those activated by dopamine were the most inhibited.
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