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  • Title: Failure of maternal antibodies to protect young turkey poults against challenge with turkey rhinotracheitis virus.
    Author: Naylor CJ, Worthington KJ, Jones RC.
    Journal: Avian Dis; 1997; 41(4):968-71. PubMed ID: 9454934.
    Abstract:
    Groups of turkey poults with high levels of maternal antibodies (MA+) to turkey rhinotracheitis virus (TRTV) were challenged with virulent TRTV at 1, 5, and 10 days of age. A maternal antibody-free group (MA-) was also challenged at 1 day of age. Before each challenge, levels of maternal antibodies to TRTV were measured by enzyme-linked immunosorbent assay. Clinical signs were scored for each group. Unchallenged poults showed no signs. Respiratory signs in poults infected at 10 days of age resembled those seen in MA- birds infected at 1 day of age but both were more severe than in MA+ birds infected at 1 day of age, when the maternal antibodies were highest. However, overall, the presence of high levels of maternal antibodies did not prevent the development of clinical disease.
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