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  • Title: Etiology of AIDS-related Kaposi's sarcoma and lymphoma.
    Author: Boshoff C, Whitby D, Talbot S, Weiss RA.
    Journal: Oral Dis; 1997 May; 3 Suppl 1():S129-32. PubMed ID: 9456674.
    Abstract:
    Kaposi's sarcoma (KS) and non-Hodgkin's lymphomas (NHL) are common consequences of HIV infection. These tumours appear to be precipitated by herpesviruses. Epstein-Barr virus (EBV) is implicated as a cause of up to 50% of systemic NHLs and up to 100% of central nervous system lymphomas in patients with AIDS. KS may be a consequence of the newly identified gamma-herpesvirus KSHV (KS-associated herpesvirus or HHV-8). This herpesvirus is found in all KS biopsies from different epidemiologic forms of this disease. KSHV is also implicated in the pathogenesis of a rare form of B cell lymphoma called body-cavity based lymphoma or primary effusion lymphoma (PEL).
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