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  • Title: Novel bromopyrrole alkaloids from the sponge Agelas dispar.
    Author: Cafieri F, Fattorusso E, Taglialatela-Scafati O.
    Journal: J Nat Prod; 1998 Jan; 61(1):122-5. PubMed ID: 9461661.
    Abstract:
    Further investigation of the Caribbean marine sponge Agelas dispar for biologically active constituents has led to the isolation of the novel bromopyrrole alkaloids longamide B (1), and clathramides C (2) and D (3), whose structures have been determined by spectroscopic methods. Isolation of the known keramadine (4) and of the ecdysonic sterols ecdysterone (5) and ajugasterone C (6) is also reported. The antimicrobial activities of the isolated bromopyrrole alkaloids is summarized.
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