These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: The activity of thymidine phosphorylase in the uterine myomas and the myometrium in perimenopausal women.
    Author: Miszczak-Zaborska E, Greger J, Wozniak K, Kowalska-Koprek U, Pajszczyk-Kieszkiewicz T.
    Journal: Z Naturforsch C J Biosci; 1997; 52(11-12):850-4. PubMed ID: 9463943.
    Abstract:
    The activity of thymidine phosphorylase (dThdPase) in the myometrium and uterine myomas has been investigated in perimenopausal women. Differences in the activity of dThdPase have been found depending on the myoma type, menopause stage and the phase of the menstrual cycle in which the surgery was performed. The enzyme in the cytoplasmatic soluble fraction obtained at 50,000 x g was the most active in cellular leiomyomas of the follicular phase, the least in adenomyomas of the luteal phase of the menstrual cycle, whereas its activity in myometrium was always unchanged. Greater differences can be observed in the activity of dThdPase after a partial purification of the enzyme from myomas. It seems that the increase in dThdPase activity may point to its correlation with transient, premalignant tumor which may later transform into malignant forms.
    [Abstract] [Full Text] [Related] [New Search]