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  • Title: Expression of murine novel zinc finger proteins highly homologous to Drosophila ovo gene product in testis.
    Author: Masu Y, Ikeda S, Okuda-Ashitaka E, Sato E, Ito S.
    Journal: FEBS Lett; 1998 Jan 16; 421(3):224-8. PubMed ID: 9468311.
    Abstract:
    We have cloned two isoforms of cDNAs encoding novel zinc finger proteins. One form encodes a 274-amino acid protein containing an acidic amino acid and serine-rich domain and a zinc finger domain which shows high sequence homology to that of Drosophila Ovo protein. The other form encodes a 179-amino acid protein containing only the zinc finger domain. Expression of both proteins possessing an antigenic epitope in COS cells revealed that they are localized in the nucleus. The 1.3-kbp mRNAs are predominantly expressed in testis, and the expression increases from 3 weeks postnatal, implying that these proteins may play important roles in the development of the testes.
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