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  • Title: [Toxicity and antitumor activity of the antibiotic rubomycin and dipin in combination with diuretics (diacarb)].
    Author: Stepanova ES.
    Journal: Antibiotiki; 1976 Mar; 21(3):262-6. PubMed ID: 946939.
    Abstract:
    Rubomycin or dipin in combination with diacarb had higher toxicity and antitumor activity as compared to administration of the cytostatic agents alone to mice with transplanted lymphosarcoma, strain L10-1. The chemotherapeutic indices of the combinations did not differ or were somewhat lower as compared to the same indices of the cytostatic agents used alone.
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