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  • Title: [Components of the kinin system in the lymph and blood, flowing from the liver and intestines in dogs in endotoxic shock].
    Author: Zamechnik TV, Iaroshenko IF, Tiurenkov IN.
    Journal: Patol Fiziol Eksp Ter; 1997; (4):11-3. PubMed ID: 9471592.
    Abstract:
    The role of the kinin system (KS) in pathogenesis of endotoxin shock was investigated. In the lymph and blood flowing out of the small intestine and in the liver the activity of KS was measured 30, 60, 90 and 120 min after injection of the sublethel dose of endotoxin E coli 0 111 B4. The results suggest that in the lymph and blood flowing from the intestine KS activity occurs during the first minutes of endotoxin shock. In the liver KS activity was observed during the second hour of shock development followed by enhancing synthesis of KS components in the presence of KS higher activity and kinin developing function exhaustion to the end of the third hour of shock duration.
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