These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: [Disaccharidases of the small-intestinal mucosa of the rat under therapy with ifosfamide (author's transl)].
    Author: Hartwich G, Domschke W, Matzkies F.
    Journal: Arzneimittelforschung; 1976 Feb; 26(2):244-8. PubMed ID: 947207.
    Abstract:
    In rats, treatment with 3-(2-chloroethyl)-2-(2-chloroethyl-amino)-tetrahydro-2H-1,3,2-oxazaphosphorine-2-oxide (ifosfamide; Asta Z 4942) results in a decrease of intestinal disaccharidase activities concomitant with morphological alterations of the mucosa. Even after morphological restoration of the tissue, enzyme activities remain reduced for a couple of days. Examinations of patients treated with ifosfamide will show whether there are comparable effects also in man which may lead to malabsorption of disaccharidases.
    [Abstract] [Full Text] [Related] [New Search]