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  • Title: Topical ketorolac 0.5% solution for the treatment of vernal keratoconjunctivitis.
    Author: Sharma A, Gupta R, Ram J, Gupta A.
    Journal: Indian J Ophthalmol; 1997 Sep; 45(3):177-80. PubMed ID: 9475021.
    Abstract:
    The efficacy of topical ketorolac 0.5% in treatment of vernal keratoconjunctivitis (VKC) was evaluated in a randomised double-blind prospective trial in 21 patients. Ketorolac treated eyes showed 50.7% reduction in main symptoms of itching compared to 33.3% relief in placebo treated eyes after 2 weeks of treatment (p < 0.01). Photophobia, ropy discharge, and conjunctival injection also lessened by 39.9%, 31.6%, and 39.1%, respectively, in ketorolac treated eyes compared to 23.8%, 17.3%, and 20.3% in placebo group. Transient stinging sensation was observed in 3 (14.3%) patients on ketorolac therapy. This study shows efficacy of ketorolac 0.5% solution in controlling symptoms in VKC.
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