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  • Title: Changes in auxin response from mutations in an AUX/IAA gene.
    Author: Rouse D, Mackay P, Stirnberg P, Estelle M, Leyser O.
    Journal: Science; 1998 Feb 27; 279(5355):1371-3. PubMed ID: 9478901.
    Abstract:
    Transcription of the AUX/IAA family of genes is rapidly induced by the plant hormone auxin, but evidence that AUX/IAA genes mediate further responses to auxin has been elusive. Changes in diverse auxin responses result from mutations in the Arabidopsis AXR3 gene. AXR3 was shown to be a member of the AUX/IAA family, providing direct evidence that AUX/IAA genes are central in auxin signaling. Molecular characterization of axr3 gain-of-function and loss-of-function mutations established the functional importance of domains conserved among AUX/IAA proteins.
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