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  • Title: [Comparison of leukocyte filters for erythrocyte concentration].
    Author: Hiller J, Lubitz B, Dominka T, Kühnl P.
    Journal: Beitr Infusionsther Transfusionsmed; 1994; 32():20-2. PubMed ID: 9480086.
    Abstract:
    UNLABELLED: We compared the following leukocyte filter blood systems (BBS): Biotrans Bio R01 Plus, Diamed Sepacell RS-200, Pall BPF4 (log 4 filters) and Biotrans Bio R01 (log 3 filter). We evaluated the leukocyte removal, handling, the increase of free hemoglobin and the loss of red blood cells (RBC) by filtration. A total of 54 buffy-coat-reduced RBCs were suspended in 200 ml PAGGS-M, stored at +4 degrees C for 24 h and filtered subsequently. Samples were taken before storage, immediately before and after filtration to measure total and free Hb and the white blood cell (WBC) contamination. RESULTS: (1) All log 4 filters showed a comparable reduction of the WBC content per RBC concentrate. (2) Differences were observed in total filtration time and loss of RBCs: Biotrans Bio R01 Plus and Pall BPF4 yielded significantly better results than Diamed Sepacell RS-200. (3) The log 3 filter did not meet the criteria of < 5 x 10(6) WBCs per filtered unit of RBCs (as recommended by the Council of Europe).
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