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  • Title: [Metabolic and rheologic changes in long-term hypothermia of erythrocyte concentrates over 15 weeks].
    Author: Matthes G, Richter E, Tofoté U, Kucera W, Lerche D.
    Journal: Beitr Infusionsther Transfusionsmed; 1994; 32():34-40. PubMed ID: 9480121.
    Abstract:
    With a multiple washing procedure in a chloride ion-free citrate-phosphate-glucose-adenine additive solution or with storage of red blood cells in a large volume of this solution, erythrocytes can be stored for 15 weeks at 4 degrees C. After 12 weeks' storage in this chloride-free solution the red blood cell parameters (2,3-DPG, glucose, lactose) measured are as good as stored erythrocytes resuspended in SAG-Mannitol after 21 days. Rheological parameters (morphology, filterability) show a maintenance of deformability of such preserved cells up to 84 days of storage. The preservation of erythrocytes by this method has the advantage that beside the hypothermic long-term storage (potential second aHIV screening of blood donors) the blood is of better quality in the first weeks of storage.
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