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  • Title: Periodontal disease progression in type II non-insulin-dependent diabetes mellitus patients (NIDDM). Part II--Microbiological analysis using the BANA test.
    Author: Novaes AB, Gonzalez Gutierrez F, Grisi MF, Novaes AB.
    Journal: Braz Dent J; 1997; 8(1):27-33. PubMed ID: 9485634.
    Abstract:
    The periodontal condition of 30 type II non-insulin-dependent diabetic patients (NIDDM) was evaluated and compared to that of 30 non-diabetic patients (age range, 30-77 years). Glycosylated hemoglobin and fasting glucose tests were used to measure the metabolic control of the patients, and the BANA (N-benzoyl-DL-arginine-naphthylamide) test was used to analyze subgingival microbiota. At the end of the study, the diabetic group was subdivided into three groups according to the degree of diabetic control: controlled, moderately controlled and poorly controlled. The non-parametric chi square test was used for statistical analyses: BANA test--no statistically significant differences were found between the two groups when analyzed as a whole. When the diabetic patients were subdivided and compared to the control group, significance was detected (P < 0.01) in the total frequencies of the BANA scores (negative, moderately positive and positive: 1, 2, and 3, respectively) in the 5-, 6-, and 7-mm pockets and also in the 4-mm pockets in the poorly controlled group.
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