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  • Title: Radiation following chemotherapy for mediastinal Hodgkin's disease: the outcome of various doses for bulky tumors.
    Author: Eisbruch A, Kazerooni EA, Sahijdak WM, Francis IR, Lichter AS.
    Journal: Radiother Oncol; 1998 Jan; 46(1):47-9. PubMed ID: 9488127.
    Abstract:
    Twenty-one patients with bulky mediastinal disease responding to chemotherapy received consolidation with low-dose mediastinal radiation (19.8-25.2 Gy). Their 5-year mediastinal failure rate (10%) was equivalent to that of 10 similar patients who received higher doses of 30-44 Gy (20%). Low-dose radiation may be appropriate for these patients. Prospective studies are required to verify these findings.
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