These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Streptococcus pneumoniae killing rate and post-antibiotic effect of levofloxacin and ciprofloxacin.
    Author: Fuchs PC, Barry AL, Brown SD.
    Journal: J Chemother; 1997 Dec; 9(6):391-3. PubMed ID: 9491837.
    Abstract:
    In vitro killing rates for levofloxacin and ciprofloxacin for six strains of Streptococcus pneumoniae were determined by the time-kill method outlined by the NCCLS. Both drugs were bactericidal at concentrations of two and four times their respective minimum inhibitory concentrations (MICs). Levofloxacin achieved a 99.9% kill on average in 1 hour more rapidly than ciprofloxacin. Post-antibiotic effect was also determined for both drugs against the same six strains. A post-antibiotic effect for a mean of 1.2 and 1.0 hours was observed for levofloxacin and ciprofloxacin, respectively. The latter means were not considered significantly different.
    [Abstract] [Full Text] [Related] [New Search]