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  • Title: Increased serum CA19-9 in patients with xanthogranulomatous cholecystitis.
    Author: Adachi Y, Iso Y, Moriyama M, Kasai T, Hashimoto H.
    Journal: Hepatogastroenterology; 1998; 45(19):77-80. PubMed ID: 9496491.
    Abstract:
    We present three cases of xanthogranulomatous cholecystitis (XGC) with an increased serum carbohydrate antigen 19-9 (CA19-9). All of the patients were elderly females and had gallstones lodged in the neck of the gallbladder. Preoperative serum CA19-9 levels were 709 U/ml, 87 U/ml, and 400 U/ml, respectively. A cholecystectomy with or without bile duct exploration was performed, and the histological diagnosis of XGC was made. Serum CA19-9 levels fell to normal levels in two patients who recovered uneventfully, but rose again in one patient who died of cholangitis. Clinicians must remember that XGC is a possible cause of increased serum CA19-9 levels.
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