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  • Title: [Free radical oxidation in patients with hypertrophic cardiomyopathy].
    Author: Liusov VA, Gomzikova IuA.
    Journal: Ter Arkh; 1997; 69(12):44-9. PubMed ID: 9503534.
    Abstract:
    As shown by the study of 27 patients with non-obstructive form of hypertrophic cardiomyopathy (HC), this disease is associated with a significant rise in the production of active oxygen forms by leukocytes, significant changes in the activity of enzyme antioxidant defense, unchanged lipid peroxidation, high total antioxidant activity of blood plasma. The patients received a complex of natural antioxidants varying by mechanism of action and glutaminic acid. Antioxidants produced a subjective clinical response, reduced incidence of cardiac arrhythmia, improved exercise tolerance. The response becomes still better in combination of antioxidants with conventional therapeutic tools.
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